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Chd8tm1Kei
Targeted Allele Detail
Nomenclature
Symbol: Chd8tm1Kei
Name: chromodomain helicase DNA binding protein 8; targeted mutation 1, Keiichi I Nakayama
MGI ID: MGI:3530648
Synonyms: Chd8deltaSL
Gene: Chd8  Location: Chr14:52435608-52495237 bp, - strand  Genetic Position: Chr14, 26.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92968
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A PGK-lox-neo-polyA cassette replaced all of the exons in the locus. (J:92968)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 8 assay results
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chd8 Mutation:  67 strains or lines available
References
Original:  J:92968 Nishiyama M, et al., Early embryonic death in mice lacking the beta-catenin-binding protein Duplin. Mol Cell Biol. 2004 Oct;24(19):8386-94
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory