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Cacna1gtm1Stl
Targeted Allele Detail
Nomenclature
Symbol: Cacna1gtm1Stl
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit; targeted mutation 1, Susumu Tonegawa
MGI ID: MGI:3530499
Synonyms: fCav3.1
Gene: Cacna1g  Location: Chr11:94408391-94474198 bp, - strand  Genetic Position: Chr11, 58.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96099
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to flank exons 9-12 with loxP sites. Crossing with mice expressing Flp in the germ line excised an FRT-flanked neo from intron 12. (J:96099)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cacna1g Mutation:  60 strains or lines available
References
Original:  J:96099 Anderson MP, et al., Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1743-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory