About   Help   FAQ
Lama1tm1.1Ekb
Targeted Allele Detail
Nomenclature
Symbol: Lama1tm1.1Ekb
Name: laminin, alpha 1; targeted mutation 1.1, Peter Ekblom
MGI ID: MGI:3530457
Synonyms: AlphaILG4-5-
Gene: Lama1  Location: Chr17:67697265-67822645 bp, + strand  Genetic Position: Chr17, 38.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96100
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsES cells containing Lama1tm1Ekb were transfected with cre recombinase, resulting in the excision of the neo-HSV-tk cassette. A truncated protein was detected by immunoblots of ES cells. (J:96100)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lama1 Mutation:  9 strains or lines available
References
Original:  J:96100 Scheele S, et al., Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1502-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory