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F2rl1tm1Bpd
Targeted Allele Detail
Nomenclature
Symbol: F2rl1tm1Bpd
Name: coagulation factor II (thrombin) receptor-like 1; targeted mutation 1, Bruce P Damiano
MGI ID: MGI:3530061
Synonyms: Par2-, PAR-2-
Gene: F2rl1  Location: Chr13:95511732-95525240 bp, - strand  Genetic Position: Chr13, 49.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96312
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo replaced the 5' region of exon 2. Northern blot of kidneys from mutant mice demonstrated the absence of transcript. (J:96312)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any F2rl1 Mutation:  34 strains or lines available
References
Original:  J:96312 Damiano BP, et al., Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1. J Pharmacol Exp Ther. 1999 Feb;288(2):671-8
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/17/2015
MGI 5.21
The Jackson Laboratory