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Targeted Allele Detail
Symbol: Cckartm1Kym
Name: cholecystokinin A receptor; targeted mutation 1, Kyoko Miyasaka
MGI ID: MGI:3529601
Synonyms: CCK-1R-, CCK-AR-
Gene: Cckar  Location: Chr5:53697776-53707705 bp, - strand  Genetic Position: Chr5, 29.52 cM
Germline Transmission:  Earliest citation of germline transmission: J:96137
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsPart of exon 1 and all of exon 2, encoding the first 122 amino acids and the first transmembrane-spanning region, was replaced with an NLS-lacZ neo. Northern blot analysis of mutant kidneys demonstrated a complete lack of transcript.. (J:96137)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cckar Mutation:  20 strains or lines available
Original:  J:96137 Takiguchi S, et al., Role of CCK-A receptor for pancreatic function in mice: a study in CCK-A receptor knockout mice. Pancreas. 2002 Apr;24(3):276-83
All:  9 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory