Degs1^{Gt(OST368559)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Degs1^{Gt(OST368559)Lex}
• Name: delta 4-desaturase, sphingolipid 1; gene trap OST368559, Lexicon Genetics
• MGI ID: MGI:3529540
• Synonyms: Degs1^{Gt(neo)172Lex}, Des^-
• Gene: Degs1 Location: Chr1:182103529-182110366 bp, - strand Genetic Position: Chr1, 84.93 cM, cytoband H5
• Alliance: Degs1^{Gt(OST368559)Lex} page

Mutation origin

• Mutant Cell Line: OST368559
• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted between exon 1 and 2. Wester blot analysis confirmed the asbence of protein expression in fibroblasts. (J:203554)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST368559	CG638627 ; (MGI Seq Detail)	3' RACE	Chr1:182106749-182107277 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  8 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Degs1 Mutation: 24 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 7 reference(s)