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Gene trapped Allele Detail
Symbol: Ldlrap1Gt(OST149604)Lex
Name: low density lipoprotein receptor adaptor protein 1; gene trap OST149604, Lexicon Genetics
MGI ID: MGI:3529295
Synonyms: ARH-, Ldlrap1Gt(neo)98Lex
Gene: Ldlrap1  Location: Chr4:134741554-134768024 bp, - strand  Genetic Position: Chr4, 67.09 cM
Mutant Cell Line:  OST149604
Germline Transmission:  Earliest citation of germline transmission: J:102291
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
Mutation detailsA gene trap vector contained a promoterless splice acceptor sequence and a betageo, as well as a long terminal repeat, a PGK promoter and Bruton tyrosine kinase, and a splice donor sequence. RT-PCR failed to detect transcript in mutant mice. (J:102291)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ldlrap1 Mutation:  10 strains or lines available
Original:  J:102291 Harada-Shiba M, et al., Disruption of autosomal recessive hypercholesterolemia gene shows different phenotype in vitro and in vivo. Circ Res. 2004 Oct 29;95(9):945-52
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory