Trpm6^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Trpm6^tm1Lex
• Name: transient receptor potential cation channel, subfamily M, member 6; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3529130
• Synonyms: Trpm6^Betageo
• Gene: Trpm6 Location: Chr19:18727347-18869875 bp, + strand Genetic Position: Chr19, 13.21 cM
• Alliance: Trpm6^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Undefined
• Mutation details: A beta-geo cassette which includes a splice acceptor site sequence, a bacterial beta-galactosidase maker (lacZ), an internal ribosome entry site (IRES) and a neomycin resistance sequence, replaced exons 2 and 3. This results in the expression of an aberrant transcript encoding only exon 1 spliced to a beta-geo. (J:239386)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Trpm6 Mutation: 111 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 2 reference(s)