Qdpr^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Qdpr^tm1Lex
• Name: quinoid dihydropteridine reductase; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3529090
• Gene: Qdpr Location: Chr5:45591374-45607571 bp, - strand Genetic Position: Chr5, 24.9 cM
• Alliance: Qdpr^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with an IRES-lacZ/MC1 neo cassette. RT-PCR and Western blot confirmed absence of RNA and protein. (J:216352)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Qdpr Mutation: 17 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 2 reference(s)