Slc4a11^{Gt(OST443317)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Slc4a11^{Gt(OST443317)Lex}
• Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11; gene trap OST443317, Lexicon Genetics
• MGI ID: MGI:3529084
• Synonyms: Slc4a11^Gt(neo)46Lex
• Gene: Slc4a11 Location: Chr2:130526033-130539439 bp, - strand Genetic Position: Chr2, 63.24 cM
• Alliance: Slc4a11^{Gt(OST443317)Lex} page

Collapse of the membranous labyrinth in the crista ampullaris and macula sacule of Slc4a11^{Gt(OST443317)Lex}/Slc4a11^{Gt(OST443317)Lex} mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: OST443317
• Germline Transmission: Earliest citation of germline transmission: J:155513
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Gene trap vector VICTR48 was integrated in the intron after the exon containing the translation initiation codon. (J:155513)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST443317	CG661725 ; (MGI Seq Detail)	3' RACE	Chr2:130533369-130534369 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc4a11 Mutation: 50 strains or lines available

References

• Original: J:155513 Lopez IA, et al., Slc4a11 gene disruption in mice: cellular targets of sensorineuronal abnormalities. J Biol Chem. 2009 Sep 25;284(39):26882-96
• All: 3 reference(s)