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Targeted Allele Detail
Symbol: Slc17a5tm1Lex
Name: solute carrier family 17 (anion/sugar transporter), member 5; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3529082
Synonyms: sialin-
Gene: Slc17a5  Location: Chr9:78536488-78588041 bp, - strand  Genetic Position: Chr9, 43.65 cM
Germline Transmission:  Earliest citation of germline transmission: J:103485
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe first 104 nucleotides of the coding region were replaced with an IRES and beta-geo cassette. The absence of transcript expression was confirmed by RT-PCR analysis on liver extracts. The absence of protein expression was confirmed by immunhistochemistry on granule cell layer and hilar neurons of the dentate gyrus samples. (J:103485, J:158444)
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Slc17a5 Mutation:  7 strains or lines available
Phenotypic Similarity to Human Syndrome: lysosomal storage disease (J:103485)

See also, data as provided by Lexicon Genetics, Inc.

Original:  J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory