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Slc17a5tm1Lex
Targeted Allele Detail
Summary
Symbol: Slc17a5tm1Lex
Name: solute carrier family 17 (anion/sugar transporter), member 5; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3529082
Synonyms: sialin-
Gene: Slc17a5  Location: Chr9:78443770-78495323 bp, - strand  Genetic Position: Chr9, 43.65 cM
Alliance: Slc17a5tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:103485
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first 104 nucleotides of the coding region were replaced with an IRES and beta-geo cassette. The absence of transcript expression was confirmed by RT-PCR analysis on liver extracts. The absence of protein expression was confirmed by immunhistochemistry on granule cell layer and hilar neurons of the dentate gyrus samples. (J:103485, J:158444)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Slc17a5 Mutation:  26 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/26/2022
MGI 6.22
The Jackson Laboratory