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Sprtm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Sprtm1Lex
Name: sepiapterin reductase; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3528977
Gene: Spr  Location: Chr6:85133678-85137766 bp, - strand  Genetic Position: Chr6, 37.15 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131376
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spr Mutation:  1 strain or line available
References
Original:  J:131376 Takazawa C, et al., A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice--as a mouse model for Parkinson's disease. Biochem Biophys Res Commun. 2008 Mar 21;367(4):787-92
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/23/2014
MGI 5.20
The Jackson Laboratory