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Targeted Allele Detail
Symbol: Rgs11tm1Lex
Name: regulator of G-protein signaling 11; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3528953
Gene: Rgs11  Location: Chr17:26202951-26211319 bp, + strand  Genetic Position: Chr17, 13.07 cM
Rgs7tm1Cjch/Rgs7tm1Cjch Rgs11tm1Lex/Rgs11tm1Lex mice have no ERG b-waves and contain ultrastructural defects in the retinal outer plexiform layer

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:103485
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
Mutation detailsCoding exons 1 through 4 were targeted. Gene inactivation was confirmed by a lack of protein detected in immunoblot assays of retinal extracts. (J:103485, J:141120)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Rgs11 Mutation:  3 strains or lines available
See also, data as provided by Lexicon Genetics, Inc.

Original:  J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory