Mapkapk3tm1Lex
Targeted Allele Detail
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Symbol: |
Mapkapk3tm1Lex |
Name: |
mitogen-activated protein kinase-activated protein kinase 3; targeted mutation 1, Lexicon Genetics |
MGI ID: |
MGI:3528847 |
Synonyms: |
MK3-CKO |
Gene: |
Mapkapk3 Location: Chr9:107132126-107167076 bp, - strand Genetic Position: Chr9, 57.98 cM
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Alliance: |
Mapkapk3tm1Lex page
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Germline Transmission: |
Earliest citation of germline transmission:
J:117668
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S/SvEvBrd
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Project Collection: |
Lexicon
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Exons 1 and 2 including the translation start site were flanked with LoxP sites via homologous recombination.
(J:117668)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mapkapk3 Mutation: |
22 strains or lines available
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Original: |
J:117668 Ronkina N, et al., The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK. Mol Cell Biol. 2007 Jan;27(1):170-81 |
All: |
1 reference(s) |
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