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Stxbp3tm1Yt
Targeted Allele Detail
Nomenclature
Symbol: Stxbp3tm1Yt
Name: syntaxin binding protein 3; targeted mutation 1, Yoshikazu Tamori
MGI ID: MGI:3528591
Synonyms: Munc18c-
Gene: Stxbp3  Location: Chr3:108793176-108840526 bp, - strand  Genetic Position: Chr3, 47.73 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95938
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P/Ola
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA IRES-neo cassette replaced the exon containing the transcription start site. Northern and Western blot analyses confirmed the absence of transcript and protein, respectively, in mutants. (J:95938)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stxbp3 Mutation:  11 strains or lines available
References
Original:  J:95938 Kanda H, et al., Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization. J Clin Invest. 2005 Feb;115(2):291-301
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory