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Aoc3tm1Salm
Targeted Allele Detail
Nomenclature
Symbol: Aoc3tm1Salm
Name: amine oxidase, copper containing 3; targeted mutation 1, Marko Salmi
MGI ID: MGI:3528069
Synonyms: AOC3-, SSAO-, VAP-1-
Gene: Aoc3  Location: Chr11:101330606-101339430 bp, + strand  Genetic Position: Chr11, 64.72 cM, cytoband B2-B5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95656
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo replaced a portion of exon 1. RT-PCR of mutant small intestine, heart and liver confirmed absence of transcript and immunostaining demonstrated the absence of protein. (J:95656)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aoc3 Mutation:  24 strains or lines available
References
Original:  J:95656 Stolen CM, et al., Absence of the endothelial oxidase AOC3 leads to abnormal leukocyte traffic in vivo. Immunity. 2005 Jan;22(1):105-15
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory