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Tg(CTSG-RARA/ZBTB16)#Ppp
Transgene Detail
Nomenclature
Symbol: Tg(CTSG-RARA/ZBTB16)#Ppp
Name: transgene insertion, Pier Paolo Pandolfi
MGI ID: MGI:3527936
Synonyms: RARalpha-PLZF, RARA-PLZF, RARA/PLZF
Transgene: Tg(CTSG-RARA/ZBTB16)#Ppp  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CTSG-RARA/ZBTB16)#Ppp expresses 2 genes
 
Mutation detailsThe human derived RARA/ZBTB16 fusion protein was placed unter the expressional control of the human cathepsin-G promoter (CTSG). 2-36 copies of the transgene were incorporated in the DNA in a head to tail and/or tail to head configuration. Transgene expression was detected in the bone marrow. Five lines were made. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:65878)
Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:65878 He LZ, et al., Two critical hits for promyelocytic leukemia. Mol Cell. 2000 Nov;6(5):1131-41
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory