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Fth1tm1Kjt
Targeted Allele Detail
Nomenclature
Symbol: Fth1tm1Kjt
Name: ferritin heavy polypeptide 1; targeted mutation 1, Khristy J Thompson
MGI ID: MGI:3526872
Synonyms: HFRT-
Gene: Fth1  Location: Chr19:9982703-9985092 bp, + strand  Genetic Position: Chr19, 6.23 cM, cytoband A-C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158718
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by insertion of a neomycin resistance cassette replacing exon 1. Absence of protein product was confirmed by immunohistochemistry. (J:158718)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fth1 Mutation:  4 strains or lines available
References
Original:  J:158718 Thompson K, et al., Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress. J Neurosci Res. 2003 Jan 1;71(1):46-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory