About   Help   FAQ
Abi2tm1Pen
Targeted Allele Detail
Nomenclature
Symbol: Abi2tm1Pen
Name: abl-interactor 2; targeted mutation 1, Ann Marie Pendergast
MGI ID: MGI:3526871
Synonyms: Abi2-
Gene: Abi2  Location: Chr1:60409619-60481158 bp, + strand  Genetic Position: Chr1, 30.47 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95254
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exons 2 and 3 with a PGK-neo. Immunoblot of MEFs or brains from mutants demonstrated a lack of protein. (J:95254)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abi2 Mutation:  22 strains or lines available
References
Original:  J:95254 Grove M, et al., ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol. 2004 Dec;24(24):10905-22
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory