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Targeted Allele Detail
Symbol: Cx3cl1tm1Sgs
Name: chemokine (C-X3-C motif) ligand 1; targeted mutation 1, Sulpicio G Soriano
MGI ID: MGI:3526846
Synonyms: CX3CL1tm, FKN-, NTN-
Gene: Cx3cl1  Location: Chr8:94772009-94782423 bp, + strand  Genetic Position: Chr8, 46.79 cM
Germline Transmission:  Earliest citation of germline transmission: J:95634
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe majority of the coding sequence was replaced with a neomycin resistance gene. Northern blot analysis of brains from mutants confirmed the absence of transcript. (J:95634)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cx3cl1 Mutation:  4 strains or lines available
Original:  J:95634 Soriano SG, et al., Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury. J Neuroimmunol. 2002 Apr;125(1-2):59-65
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory