Sstr4^tm1Ute
Targeted Allele Detail

Summary

• Symbol: Sstr4^tm1Ute
• Name: somatostatin receptor 4; targeted mutation 1, Ute Hochgeschwenger
• MGI ID: MGI:3526677
• Gene: Sstr4 Location: Chr2:148237297-148238684 bp, + strand Genetic Position: Chr2, 73.44 cM
• Alliance: Sstr4^tm1Ute page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:95635
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 592 bp fragment covering most of the coding region was replaced with a neomycin cassette. Experiments were conducted to confirm that a null allele was produced. (J:95635)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sstr4 Mutation: 19 strains or lines available

References

• Original: J:95635 Videau C, et al., Characterisation of [125I]-Tyr0DTrp8-somatostatin binding in sst1- to sst4- and SRIF-gene-invalidated mouse brain. Naunyn Schmiedebergs Arch Pharmacol. 2003 Jun;367(6):562-71
• All: 4 reference(s)