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Sdhdtm1Jlob
Targeted Allele Detail
Nomenclature
Symbol: Sdhdtm1Jlob
Name: succinate dehydrogenase complex, subunit D, integral membrane protein; targeted mutation 1, Jose Lopez-Barneo
MGI ID: MGI:3526521
Synonyms: SDHD-
Gene: Sdhd  Location: Chr9:50596340-50603849 bp, - strand  Genetic Position: Chr9, 27.75 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95252
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 2-4 were replaced with a neomycin resistance gene. (J:95252)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sdhd Mutation:  8 strains or lines available
References
Original:  J:95252 Piruat JI, et al., The mitochondrial SDHD gene is required for early embryogenesis, and its partial deficiency results in persistent carotid body glomus cell activation with full responsiveness to hypoxia. Mol Cell Biol. 2004 Dec;24(24):10933-40
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory