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Wnt9btm1Amc
Targeted Allele Detail
Summary
Symbol: Wnt9btm1Amc
Name: wingless-type MMTV integration site family, member 9B; targeted mutation 1, Andrew P McMahon
MGI ID: MGI:3526436
Synonyms: Wnt9bcneo, Wnt9bneo
Gene: Wnt9b  Location: Chr11:103618190-103640647 bp, - strand  Genetic Position: Chr11, 67.47 cM
Alliance: Wnt9btm1Amc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100575
Parent Cell Line:  AV3 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, Hypomorph)
Mutation:    Insertion
 
Mutation detailsA targeting construct was designed to insert loxP sites into introns 1 and 2 to flank exon 2. An FRT-flanked neo was inserted upstream of the intron 2 loxP site. This allele is hypomorphic. (J:100575)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt9b Mutation:  22 strains or lines available
References
Original:  J:100575 Carroll TJ, et al., Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug;9(2):283-92
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory