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Wnt7btm2Amc
Targeted Allele Detail
Nomenclature
Symbol: Wnt7btm2Amc
Name: wingless-type MMTV integration site family, member 7B; targeted mutation 2, Andrew P McMahon
MGI ID: MGI:3526432
Synonyms: Wnt7bC3
Gene: Wnt7b  Location: Chr15:85535437-85581821 bp, - strand  Genetic Position: Chr15, 40.39 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134483
Parent Cell Line:  AV3 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 3 was floxed and an frt flanked PGK-neo cassette was inserted downstream of exon 3. (J:134483)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt7b Mutation:  13 strains or lines available
References
Original:  J:134483 Rajagopal J, et al., Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development. 2008 May;135(9):1625-34
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory