Wnt7b^tm1Amc
Targeted Allele Detail

Summary

• Symbol: Wnt7b^tm1Amc
• Name: wingless-type MMTV integration site family, member 7B; targeted mutation 1, Andrew P McMahon
• MGI ID: MGI:3526431
• Gene: Wnt7b Location: Chr15:85419638-85466022 bp, - strand Genetic Position: Chr15, 40.39 cM
• Alliance: Wnt7b^tm1Amc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101493
• Parent Cell Line: AV3 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted downstream of exon 1 and an additional loxP site was inserted upstream of exon 1. (J:101493)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wnt7b Mutation: 17 strains or lines available

References

• Original: J:101493 Lobov IB, et al., WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature. 2005 Sep 15;437(7057):417-21
• All: 1 reference(s)