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Dlk1tm1Srba
Targeted Allele Detail
Nomenclature
Symbol: Dlk1tm1Srba
Name: delta like non-canonical Notch ligand 1; targeted mutation 1, Steven R Bauer
MGI ID: MGI:3526402
Gene: Dlk1  Location: Chr12:109452823-109463336 bp, + strand  Genetic Position: Chr12, 60.17 cM, cytoband E-F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:145076
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-3 of this imprinted gene were replaced with a neomycin resistance cassette. No mRNA from this locus was detected in the neonatal liver of homozygotes or in heterozygotes that have paternally-inherited the mutant allele. (J:145076)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dlk1 Mutation:  15 strains or lines available
References
Original:  J:145076 Raghunandan R, et al., Dlk1 influences differentiation and function of B lymphocytes. Stem Cells Dev. 2008 Jun;17(3):495-507
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory