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Fgf10tm1.1Sms
Targeted Allele Detail
Nomenclature
Symbol: Fgf10tm1.1Sms
Name: fibroblast growth factor 10; targeted mutation 1.1, Suzanne L Mansour
MGI ID: MGI:3526181
Gene: Fgf10  Location: Chr13:118714699-118792573 bp, + strand  Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150706
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA Neo+KanR cassette was placed in intron 1 and exon 2 was flanked by loxP sites. Exon 2 was subsequently removed by cre-mediated recombination. (J:150706)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf10 Mutation:  10 strains or lines available
References
Original:  J:150706 Abler LL, et al., Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung. Dev Dyn. 2009 Jul 17;238(8):1999-2013
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory