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Rb1cc1tm1.1Guan
Targeted Allele Detail
Nomenclature
Symbol: Rb1cc1tm1.1Guan
Name: RB1-inducible coiled-coil 1; targeted mutation 1.1, Jun-Lin Guan
MGI ID: MGI:3526069
Synonyms: Fip200flox
Gene: Rb1cc1  Location: Chr1:6214634-6276375 bp, + strand  Genetic Position: Chr1, 1.89 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114498
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 4 and 5 were flanked by loxP sites. (J:114498)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 9 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rb1cc1 Mutation:  4 strains or lines available
References
Original:  J:114498 Gan B, et al., Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. J Cell Biol. 2006 Oct 9;175(1):121-33
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory