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Gene trapped Allele Detail
Symbol: Cdh2Gt(OST49160)Lex
Name: cadherin 2; gene trap OST149160, Lexicon Genetics
MGI ID: MGI:3525642
Synonyms: Cdh2Gt(Beta-geo)1Glr, NcadlacZ
Gene: Cdh2  Location: Chr18:16588877-16809246 bp, - strand  Genetic Position: Chr18, 10.1 cM
Mutant Cell Line:  OST49160 (Lexicon Genetics)
Germline Transmission:  Earliest citation of germline transmission: J:95209
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
Mutation detailsA gene trap vector containing flanking long terminal repeats, a splice acceptor, and Beta-geo fusion gene inserted 427 bp downstream of exon 1. Western blot of protein lysates indicated that no wild-type protein was present. Beta-galactosidase staining showed that expression of the mutant allele matched that of Cadh2 expression. (J:95209)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdh2 Mutation:  17 strains or lines available
Original:  J:95209 Luo Y, et al., N-cadherin is not essential for limb mesenchymal chondrogenesis. Dev Dyn. 2005 Feb;232(2):336-44
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory