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Il27ratm1Fjs
Targeted Allele Detail
Nomenclature
Symbol: Il27ratm1Fjs
Name: interleukin 27 receptor, alpha; targeted mutation 1, Frederic J de Sauvage
MGI ID: MGI:3525439
Synonyms: IL27-R-, Il27ra-, TCCR-
Gene: Il27ra  Location: Chr8:84030294-84042589 bp, - strand  Genetic Position: Chr8, 40.26 cM, cytoband C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65439
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exons 2-8. Splenic RNA analyzed by Northern blot and RT-PCR showed no transcript was expressed from this allele. (J:65439)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il27ra Mutation:  11 strains or lines available
References
Original:  J:65439 Chen Q, et al., Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature. 2000 Oct 19;407(6806):916-20
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory