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Als2tm1Cai
Targeted Allele Detail
Nomenclature
Symbol: Als2tm1Cai
Name: amyotrophic lateral sclerosis 2 (juvenile); targeted mutation 1, Huaibin Cai
MGI ID: MGI:3522476
Synonyms: ALS2-
Gene: Als2  Location: Chr1:59162926-59237231 bp, - strand  Genetic Position: Chr1, 29.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100336
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Als2 Mutation:  21 strains or lines available
References
Original:  J:100336 Cai H, et al., Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress. J Neurosci. 2005 Aug 17;25(33):7567-74
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory