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Sat1tm1Alh
Targeted Allele Detail
Nomenclature
Symbol: Sat1tm1Alh
Name: spermidine/spermine N1-acetyl transferase 1; targeted mutation 1, Leena Alhonen
MGI ID: MGI:3521903
Synonyms: SSAT-ko
Gene: Sat1  Location: ChrX:155213132-155216449 bp, - strand  Genetic Position: ChrX, 72.38 cM, cytoband F3-F4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99381
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA SmaI fragment containing part of exon 1 was replaced with a neomycin resistance cassette. Western blot analysis indicated the absence of protein product. (J:77802)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sat1 Mutation:  3 strains or lines available
References
Original:  J:99381 Tucker JM, et al., Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase. Cancer Res. 2005 Jun 15;65(12):5390-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory