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Adcyap1tm1Clw
Targeted Allele Detail
Nomenclature
Symbol: Adcyap1tm1Clw
Name: adenylate cyclase activating polypeptide 1; targeted mutation 1, Christopher S Colwell
MGI ID: MGI:3521845
Synonyms: PACAP-
Gene: Adcyap1  Location: Chr17:93199422-93205485 bp, + strand  Genetic Position: Chr17, 60.67 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94880
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3, 4 and part of 5 were replaced with a neomycine resistance cassette. RIA analysis confirmed the absence of protein product. (J:94880)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adcyap1 Mutation:  10 strains or lines available
References
Original:  J:94880 Colwell CS, et al., Selective deficits in the circadian light response in mice lacking PACAP. Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1194-201
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory