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Tg(Alb1-HBV)66Bri
Transgene Detail
Nomenclature
Symbol: Tg(Alb1-HBV)66Bri
Name: transgene insertion 66, Ralph L Brinster
MGI ID: MGI:3513825
Synonyms: 107-5D, Alb-PSX, HBsAg, Tg[Alb-1,HBV]Bri66
Transgene: Tg(Alb1-HBV)66Bri  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/10 x DBA/2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA BglIIA fragment of HBV subtype ayw spanning nucleotides 239-1986 encoding the entire HBV envelope coding region was placed under the constitutive transcriptional control of the mouse albumin promoter. (J:94540)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:94540 Chisari FV, et al., Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice. J Virol. 1986 Dec;60(3):880-7
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory