Mrfap1^tm1Kto
Targeted Allele Detail

Summary

• Symbol: Mrfap1^tm1Kto
• Name: Morf4 family associated protein 1; targeted mutation 1, Kaoru Tominaga
• MGI ID: MGI:3513671
• Synonyms: Pam14^-
• Gene: Mrfap1 Location: Chr5:36952211-36954098 bp, - strand Genetic Position: Chr5, 19.26 cM
• Alliance: Mrfap1^tm1Kto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92967
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with a PGK-Hprt cassette. Northern blot analysis confirmed the absence of transcription products. Protein product could not be detected by Wesern blot analysis.

Expression

In Mice Carrying this Mutation:

22 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrfap1 Mutation: 5 strains or lines available

References

• Original: J:92967 Tominaga K, et al., PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice. Mol Cell Biol. 2004 Oct;24(19):8366-73
• All: 1 reference(s)