About   Help   FAQ
Crhbptm1Afs
Targeted Allele Detail
Nomenclature
Symbol: Crhbptm1Afs
Name: corticotropin releasing hormone binding protein; targeted mutation 1, Audrey F Seasholtz
MGI ID: MGI:3513042
Gene: Crhbp  Location: Chr13:95431376-95444831 bp, - strand  Genetic Position: Chr13, 49.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57963
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe translated portion of exon 1 and all of exons 2-5 were replaced with a PGK-neomycin resistance cassette. In situ hybridization confirmed the absence of transcripts in the cerebral cortex. (J:57963)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crhbp Mutation:  11 strains or lines available
References
Original:  J:57963 Karolyi IJ, et al., Altered anxiety and weight gain in corticotropin-releasing hormone-binding protein-deficient mice. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11595-600
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory