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Lgr5tm1Ah
Targeted Allele Detail
Nomenclature
Symbol: Lgr5tm1Ah
Name: leucine rich repeat containing G protein coupled receptor 5; targeted mutation 1, Aaron Hsueh
MGI ID: MGI:3512420
Synonyms: LGR5-, Lgr5-lacZ, Lgr5tm1Lex
Gene: Lgr5  Location: Chr10:115450311-115587780 bp, - strand  Genetic Position: Chr10, 63.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94196
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 120 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lgr5 Mutation:  4 strains or lines available
References
Original:  J:94196 Morita H, et al., Neonatal lethality of LGR5 null mice is associated with ankyloglossia and gastrointestinal distension. Mol Cell Biol. 2004 Nov;24(22):9736-43
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory