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Rac3tm1Hkp
Targeted Allele Detail
Nomenclature
Symbol: Rac3tm1Hkp
Name: RAS-related C3 botulinum substrate 3; targeted mutation 1, Nora C Hesterkamp
MGI ID: MGI:3512107
Gene: Rac3  Location: Chr11:120721470-120723969 bp, + strand  Genetic Position: Chr11, 84.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99168
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region was replaced with a PGK-NEO cassette. QRT-PCR confirmed the absence of gene products. (J:99168)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rac3 Mutation:  9 strains or lines available
References
Original:  J:99168 Cho YJ, et al., Generation of rac3 Null Mutant Mice: Role of Rac3 in Bcr/Abl-Caused Lymphoblastic Leukemia. Mol Cell Biol. 2005 Jul;25(13):5777-85
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory