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Aldh1a3tm1Gdu
Targeted Allele Detail
Nomenclature
Symbol: Aldh1a3tm1Gdu
Name: aldehyde dehydrogenase family 1, subfamily A3; targeted mutation 1, Gregg Duester
MGI ID: MGI:3512079
Synonyms: Raldh3-
Gene: Aldh1a3  Location: Chr7:66390890-66427517 bp, - strand  Genetic Position: Chr7, 35.73 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108515
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 11 was removed via cre mediated recombination. Retinoic acid activity was absent from the ventral retina and olfactory pit at E10.5. (J:108515)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aldh1a3 Mutation:  14 strains or lines available
References
Original:  J:108515 Molotkov A, et al., Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. Development. 2006 May;133(10):1901-10
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory