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Tg(Ela1-Myc)158Bri
Transgene Detail
Summary
Symbol: Tg(Ela1-Myc)158Bri
Name: transgene insertion 158, Ralph L Brinster
MGI ID: MGI:3511172
Synonyms: 1194-2, Tg(Ela-1,Myc)Bri158
Transgene: Tg(Ela1-Myc)158Bri  Location: unknown  
Alliance: Tg(Ela1-Myc)158Bri page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ela1-Myc)158Bri expresses 1 gene
 
Mutation details2.7 kb XbaI-XhoI fragment of murine Myc containing the entire protein coding region within exons 2 and 3 was placed under the regulation of the enhancer and promoter sequence of the rat elastase 1 gene. The human growth hormone gene Sma donated the 3'UTR and poly adenylation sequence in this construct. Transgene expression was detected in the pancreas. (J:76992)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Tumor Data
List all tumor models in MMHCdb carrying Tg(Ela1-Myc)158Bri
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:76992 Sandgren EP, et al., Pancreatic tumor pathogenesis reflects the causative genetic lesion. Proc Natl Acad Sci U S A. 1991 Jan 1;88(1):93-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory