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Targeted Allele Detail
Symbol: Traf3ip2tm1Lix
Name: TRAF3 interacting protein 2; targeted mutation 1, Xiaoxia Li
MGI ID: MGI:3510783
Synonyms: Act1flox
Gene: Traf3ip2  Location: Chr10:39612934-39655307 bp, + strand  Genetic Position: Chr10, 20.86 cM
Germline Transmission:  Earliest citation of germline transmission: J:93923
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA targeting vector was designed to flank exon 2 with loxP sites as well as insert a neomycin resistance gene and an additional 5' loxP site into intron 1. (J:93923)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Traf3ip2 Mutation:  20 strains or lines available
Original:  J:93923 Qian Y, et al., Act1, a negative regulator in CD40- and BAFF-mediated B cell survival. Immunity. 2004 Oct;21(4):575-87
All:  6 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory