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Gp1bbtm1Ware
Targeted Allele Detail
Nomenclature
Symbol: Gp1bbtm1Ware
Name: glycoprotein Ib, beta polypeptide; targeted mutation 1, Jerry Ware
MGI ID: MGI:3510459
Synonyms: GP IbbetaNull
Gene: Gp1bb  Location: Chr16:18620319-18622403 bp, - strand  Genetic Position: Chr16, 11.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93756
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A targeting vector was designed to replace codons in exon 2 with a neomycin resistance gene. (J:93756)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gp1bb Mutation:  4 strains or lines available
Notes
ES cell line = DS2A.

References
Original:  J:93756 Kato K, et al., Genetic deletion of mouse platelet glycoprotein Ibbeta produces a Bernard-Soulier phenotype with increased alpha-granule size. Blood. 2004 Oct 15;104(8):2339-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory