About   Help   FAQ
Ntrk1tm1Tes
Targeted Allele Detail
Nomenclature
Symbol: Ntrk1tm1Tes
Name: neurotrophic tyrosine kinase, receptor, type 1; targeted mutation 1, Lino Tessarollo
MGI ID: MGI:3505767
Synonyms: TrkA-, TrkAneo
Gene: Ntrk1  Location: Chr3:87778244-87795162 bp, - strand  Genetic Position: Chr3, 38.62 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93578
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed PGK-neopA was inserted into intron 11. Northern blot and RT-PCR indicated a lack of transcript in dorsal root ganglia of mutants. Upon cre-mediated recombination, expression of the gene is restored. (J:93578)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntrk1 Mutation:  33 strains or lines available
References
Original:  J:93578 Coppola V, et al., Ablation of TrkA function in the immune system causes B cell abnormalities. Development. 2004 Oct;131(20):5185-95
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory