About   Help   FAQ
Transgene Detail
Symbol: Tg(CAG-Bgeo/ALPP)1Lbe
Name: transgene insertion 1, Corrinne Lobe
MGI ID: MGI:3505556
Synonyms: Tg(ACTB-Bgeo/ALPP)1Lbe, Tg(CAG-Bgeo/ALPP)1Lbe, ZAP, Z/AP
Transgene: Tg(CAG-Bgeo/ALPP)1Lbe  Location: unknown  
Germline Transmission:  Earliest citation of germline transmission: J:93700
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsThe transgene contains the CMV enhancer/chicken beta-actin promoter, a floxed Beta-geo reporter/SV40 polyadenylation signal segment, and the human placental alkaline phosphatase gene followed by a rabbit Hbb polyadenylation sequence. In transgenic mice expression of lacZ is widespread, with notable exceptions being erythrocytes, chondrocytes and adipocytes. This expression is observed throughout all embryonic and adult stages. (J:93700)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Cre excision of lacZ and the neomycin resistance gene results in expression of the ALPP reporter.
Original:  J:93700 Lobe CG, et al., Z/AP, a double reporter for cre-mediated recombination. Dev Biol. 1999 Apr 15;208(2):281-92
All:  142 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.19
The Jackson Laboratory