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Myf6tm1(cre)Mrc
Targeted Allele Detail
Nomenclature
Symbol: Myf6tm1(cre)Mrc
Name: myogenic factor 6; targeted mutation 1, Mario R Capecchi
MGI ID: MGI:3487371
Synonyms: Myf6-Cre, Myf6ICNm, Myf6-NN-
Gene: Myf6  Location: Chr10:107492860-107494729 bp, - strand  Genetic Position: Chr10, 55.96 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93444
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation details
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myf6     Summary of all recombinase alleles driven by Myf6.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myf6 Mutation:  2 strains or lines available
Notes
Expression of the endogenous gene is normal.

References
Original:  J:93444 Keller C, et al., Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. Genes Dev. 2004 Dec 1;18(21):2614-26
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory