Dp(16Cbr1-Fam3b)1Rhr
Targeted Allele Detail
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Symbol: |
Dp(16Cbr1-Fam3b)1Rhr |
Name: |
duplication, Chr 16, R H Reeves 1 |
MGI ID: |
MGI:3487283 |
Synonyms: |
Dp(16Cbr1-ORF9)1Rhr, Ts1Rhr |
Gene: |
Dp(16Cbr1-Fam3b)1Rhr Location: Chr16:93404725-97306136 bp Genetic Position: Chr16, Syntenic
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Germline Transmission: |
Earliest citation of germline transmission:
J:93223
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Parent Cell Line: |
MC1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Inserted expressed sequence) |
Mutation: |
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Duplication
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Dp(16Cbr1-Fam3b)1Rhr involves 68 genes/genome features (Gm15341, Gm15317, Gm22344 ...)
View all
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Mutation details: A duplication of a 3.9 Mb region on chromosome 16 was engineered by Cre-mediated recombination between inserted loxP sites located on different chromosomes. This duplicated segment contains mouse orthologs of 33 conserved and minimally conserved genes in the human Down syndrome critical region.
(J:93223)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Carrying any Dp(16Cbr1-Fam3b)1Rhr Mutation: |
1 strain or line available
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Original: |
J:93223 Olson LE, et al., A chromosome 21 critical region does not cause specific down syndrome phenotypes. Science. 2004 Oct 22;306(5696):687-90 |
All: |
30 reference(s) |
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