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MaoaK284stop
Spontaneous Allele Detail
Nomenclature
Symbol: MaoaK284stop
Name: monoamine oxidase A; K284stop
MGI ID: MGI:3057337
Synonyms: MaoaA863T, MAO A KO
Gene: Maoa  Location: ChrX:16619698-16687818 bp, + strand  Genetic Position: ChrX, 11.78 cM, cytoband A2
Mutation
origin
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
    A transversion at nucleotide 863 in exon 8 created a stop codon at residue 284 rather than a lysine. (J:93356, J:136818)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Maoa Mutation:  12 strains or lines available
References
Original:  J:93356 Chen K, et al., A spontaneous point mutation produces monoamine oxidase A/B knock-out mice with greatly elevated monoamines and anxiety-like behavior. J Biol Chem. 2004 Oct 17;279(38):39645-52
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory