About   Help   FAQ
MaoaK284stop
Spontaneous Allele Detail
Nomenclature
Symbol: MaoaK284stop
Name: monoamine oxidase A; K284stop
MGI ID: MGI:3057337
Synonyms: MaoaA863T, MAO A KO
Gene: Maoa  Location: ChrX:16485937-16554051 bp, + strand  Genetic Position: ChrX, 11.78 cM, cytoband A2
Mutation
origin
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
    An A-to-T at coding nucleotide 850 in exon 8 created a stop codon at lysine codon 284 (p.K284*). (J:93356, J:136818)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Maoa Mutation:  10 strains or lines available
References
Original:  J:93356 Chen K, et al., A spontaneous point mutation produces monoamine oxidase A/B knock-out mice with greatly elevated monoamines and anxiety-like behavior. J Biol Chem. 2004 Oct 17;279(38):39645-52
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory