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Tg(Prnp-SNCA*A53T)83Vle
Transgene Detail
Nomenclature
Symbol: Tg(Prnp-SNCA*A53T)83Vle
Name: transgene insertion 83, Virginia M-Y Lee
MGI ID: MGI:3057167
Synonyms: A53T alpha-synuclein PRP, alphaS+, M83, PrP-alpha-syn mice (line M83), Tg(SNCA)83Vle
Transgene: Tg(Prnp-SNCA*A53T)83Vle  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6 x C3H
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
This line was originally designated M83. Line M91 was also generated.

References
Original:  J:76657 Giasson BI, et al., Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron. 2002 May 16;34(4):521-33
All:  30 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory